Product Description
Cell Gain + HOT: Intermittent Hyperoxia Hypoxia Training with High Oxygen% Training
R&D Grade Training Oxygen Concentrator & Open Knowledge Project
Cellular empowerment by leveraging Nobel Prize winning technology.
If you want to support climate change reversal & you are into longevity, biohacking, overall health, hyperbaric chambers, are a top performing athlete, or a couch potato our R&D grade training equipment is for you. In a nutshell, our equipment and citizen science project for Intermittent Hyperoxia-Hypoxia Training (IHHT) enhanced with High Oxygen% Training (HOT) is meant to increase your body cells' power and your energy with cutting edge technology yet using zero (non-air) chemicals, peptides, drugs or medicines.
Instead of building a "Not a flame thrower" (Elon Musk's controversial funding campaign) to fund the development of the global Net+Positive Energy ecosystem, we decided to make a funding product that is beneficial for human health and energy, namely IHHT and IHHT+HOT. If you as our contributor would like to contribute with more than the value of one IHHT(+HOT), we extend the option to donate our devices to your favorite causes/organizations for their affiliates to use or as a means of income (see Business Oriented contributors section).
The mitochondria is the energy producing organelle of our cells and our bodies, commonly referred to as the cells' powerhouse. If your cells are low on power, you are low on power. Just as you would train in the gym to strengthen your muscles, you can also train your cells for more power with CellGain IHHT(+HOT) — an improved altitude "sherpa-like training" without the high altitude headaches!
The IHHT advantage is that we can train our cells even while sitting down or resting (or after a few sessions while doing exercise). That is why we prefer that our contributors read the benefits of IHHT directly from peer reviewed scientific literature (see Bibliography section).
How Does It Work?
Just as we improve our muscle strength by challenging our muscles with more weight, IHHT+HOT challenges the cells' powerhouse (mitochondria) with sets of breathing lower oxygen content air (hypoxia). Like a typical gym session, an IHHT+HOT session lasts between 30 minutes to one hour.
Instead of resting between sets, in IHHT+HOT we supplement our cells with an enhanced recharge cycle using oxygen rich air (hyperoxia) in between hypoxic air — sort of like massaging the muscles in between sets. During a typical IHHT+HOT session one would expect to start breathing concentrated oxygen (increasing SpO2 to ≈100%), then hypoxic air (decreasing SpO2), then return to concentrated oxygen, and so the cycles continue until end of training.
Revitalizing From the Bottom Up
Our cells convert energy in the mitochondria to function properly. The more energy at their disposal the better they work, and by extension so does our bodies. Our cells' mitochondria cleaning signal is activated by the low SpO2 phase, recycling "defective" mitochondria. Then the cells are additionally stimulated to produce new and healthy mitochondria during the high SpO2 phase.
IHHT+HOT could be seen as an indirect analogy to the biochemical signaling produced when changing quickly between hot sauna and cold plunges — but without the extreme uncomfortable experience.
Research Areas
Recent peer-reviewed literature explores IHHT (although not yet IHHT+HOT) in relation to:
- IHHT & metabolic health
- IHHT & (including geriatric) cognition
- IHHT & overall wellness
- IHHT & obesity
- IHHT & athletic performance
- IHHT & cholesterol
- IHHT & COVID
- IHHT & necrosis (gangrene)
- IHHT & cancer
- IHHT & glucose in the body
Note on usage: Just as one could overdo muscle training, one could also overdo IHHT. Our R&D training units will include safety guidelines responding to your body's O2 content (Beginner / Intermediate / Advanced modes). Please train with partners, especially when trying new settings.
Why IHHT+HOT?
Would you rather be up to date with the latest health and wellness knowledge, or wait several years to see it?
We are developing IHHT with High Oxygen Training (HOT). Exercising with intermittent HyperBaric Oxygen Therapy (HBOT) has shown preliminary positive correlations to lead life indicators believed to correlate with health and lifespan. IHHT+HOT resides in the oxygen concentrations between IHHT and iHBOT — without the risks (fires, claustrophobia, entrapment) or costs ($30k–$150k) of pressurized enclosures.
Our Two Hypotheses
If IHHT has been researched for health and life quality correlated indicators and iHBOT showed improved health and lifespan correlated indicators, could IHHT+HOT have a significant beneficial impact on all or most of those indicators? Could the inconveniences and costs of pressurized enclosures be discarded while producing even better results than IHHT without HOT?
Additional Future Research Areas (IHHT+HOT)
- Top performing athletes (e.g. logging performance outcomes)
- Geriatric wards (overall wellbeing, mental/physical exercises)
- Combining IHHT(+HOT) with red or infrared light
- Combining IHHT+HOT with sauna
- Combining IHHT(+HOT) before/after HBOT/iHBOT
- Investigating IHHT+HOT impact on areas where IHHT has been researched
IHHT+HOT is still not extensively researched for health and wellness. That is why we want to enable all citizen scientists, scientists, and professionals to explore the effects of IHHT+HOT with a system that delivers the required training oxygen concentrations on the spot with ease of mobility around the gym, house, lab, resort, or wellness practice.
Product Development Roadmap
"Prototypes are easy, production is complex." That is why we are currently collecting pre-orders at early bird discounted prices. We aim to maximize functionality and user-friendliness. Having previously developed gas-tailoring units (high ozone "plasma activated oxygen" gas, liquids and oils), applying those lessons to human health comes naturally.
We are confident to start shipping CellGain IHHT+HOT units in about 6 months. Early delivery is possible — contributors will have the option to opt-in as early trial customers with additional perks.
Touchscreen UI Features
- Multiple user settings & preferences
- Training track record & session history
- Initial user calibration
- Relaxed start (programmable hyperoxia warm-up)
- Pre-programmed cycles adjustable by SpO2 levels
For Business-Minded Backers
An IHHT session in the US costs between $120–$200 USD. A CellGain IHHT+HOT ($18,000 USD pre-order) can break even in less than two months of sessions (100–180 hours), while delivering more benefits than IHHT alone.
Ideal for: gym owners, spas & resorts, HBOT professionals, personal trainers, wellness centers, longevity professionals, medical practitioners, think tanks, as well as longevity enthusiasts, and biohackers. If you are their member or regular and would like to try it as well, please share this link with them.
Pre-Order Pricing
- Cell Gain IHHT+HOT Early Bird Pre-Order: $18,000 USD (Steady state: ~$20,000+ USD) — Ships in ~6 months or less. First order receive an additional discount.
We are targeting $60,000 USD in pre-orders to iterate fast on production-ready components for 3–6 units. Units combining on-demand HOT and IHHT are not yet available on the market. Our mission is to bring it to you first!
(For comparisons sake, "decent" IHHT units without HOT from Europe cost $20,000–$30,000 USD plus up to $4,000 USD of shipping and imports)
Funding Stretch Goals
- $100k USD: App integration — session progression metrics, exercise routine integration, reminder alarms, and data export features. [Wireless connectivity not being considered at the moment for security reasons]
- $150k USD: Double the first production run and double early-bird units. Cognitive/response time measuring features during IHHT(+HOT) training.
- $200k USD: Community research database + continuous software updates. Results may be published including your name, organization, or business.
- $400k+ USD: Explore integration of additional breathable gas technologies to our units.
Bibliography
- 2019 Nobel Prize in Physiology or Medicine — HIF (Hypoxia Inducible Factors) — William G. Kaelin Jr., Sir Peter J. Ratcliffe, and Gregg L. Semenza.
- 1. Effectiveness of Intermittent Hypoxia-Hyperoxia Therapy in Different Pathologies with Possible Metabolic Implications.
- 2. Effects of Intermittent Hypoxia in Training Regimes and in Obstructive Sleep Apnea on Aging Biomarkers and Age-Related Diseases: A Systematic Review.
- 3. Hyperbaric Oxygen Therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial.
Disclaimer: CellGain IHHT and CellGain IHHT+HOT are wellness, training, and research devices. They are not medical devices and are not licensed nor intended to diagnose, treat, cure or prevent any disease. They are not a replacement for medication, medical treatment, or a doctor's examination. Always consult your physician before use and, where applicable, also consult with your certified medical principal investigator. For research, training, and wellness purposes only. Scientific claims in cited scientific literature or external search engines are not corroborated nor validated by the FDA, AII&HEALTH, nor AII+X. AII&HEALTH and AII+X do not endorse or verify the veracity of any claims made on external webpages, and are not responsible for any opinion, advice, information, or statements made by third parties, including scientific literature.